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Moskowitz, Ivan

One or more keywords matched the following properties of Moskowitz, Ivan

Property	Value
keywords	Genetics
keywords	Genetics, Molecular

One or more keywords matched the following items that are connected to Moskowitz, Ivan

Item Type	Name
Concept	Mice, Inbred C3H
Concept	Mice, Transgenic
Concept	Mice, Inbred C57BL
Concept	Mice, Knockout
Concept	Mice
Concept	Mice, 129 Strain
Concept	Mice, Mutant Strains
Academic Article	Comparison of two murine models of familial hypertrophic cardiomyopathy.
Academic Article	Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.
Academic Article	Cardiac electrophysiological phenotypes in postnatal expression of Nkx2.5 transgenic mice.
Academic Article	The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.
Academic Article	Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.
Academic Article	A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development.
Academic Article	Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
Academic Article	Characterization of sinoatrial node in four conduction system marker mice.
Academic Article	Complex genomic rearrangement in CCS-LacZ transgenic mice.
Academic Article	The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy.
Academic Article	A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines.
Academic Article	Genome-wide identification of mouse congenital heart disease loci.
Academic Article	A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus.
Academic Article	TBX5 drives Scn5a expression to regulate cardiac conduction system function.
Academic Article	E2F3 plays an essential role in cardiac development and function.
Academic Article	Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]
Academic Article	Complex interactions between genes controlling trafficking in primary cilia.
Academic Article	Defective sumoylation pathway directs congenital heart disease.
Academic Article	Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease.
Academic Article	Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
Academic Article	sonic hedgehog is required in pulmonary endoderm for atrial septation.
Academic Article	DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
Academic Article	Inducible recombination in the cardiac conduction system of minK: CreERT² BAC transgenic mice.
Academic Article	Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.
Academic Article	Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis.
Academic Article	Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects.
Academic Article	Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation.
Academic Article	MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus.
Academic Article	Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development.
Academic Article	A common genetic variant within SCN10A modulates cardiac SCN5A expression.
Academic Article	The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model.
Academic Article	The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation.
Academic Article	De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects.
Academic Article	Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm.
Academic Article	Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Academic Article	Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation.
Academic Article	Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm.
Academic Article	A promoter interaction map for cardiovascular disease genetics.
Academic Article	Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development.
Academic Article	A calcium transport mechanism for atrial fibrillation in Tbx5-mutant mice.
Academic Article	Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development.
Academic Article	Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis.
Academic Article	Enhancer transcription identifies cis-regulatory elements for photoreceptor cell types.
Academic Article	Transcriptional Patterning of the Ventricular Cardiac Conduction System.
Academic Article	ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
Academic Article	Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation.
Academic Article	Chamber-specific transcriptional responses in atrial fibrillation.
Academic Article	Identification of direct transcriptional targets of NFATC2 that promote ß cell proliferation.
Academic Article	Tbx5 drives Aldh1a2 expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development.
Academic Article	Detecting critical transition signals from single-cell transcriptomes to infer lineage-determining transcription factors.
Academic Article	Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.
Academic Article	Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.
Academic Article	Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization.
Grant	A Screen for Mouse Cardiovascular Morphogenesis Mutants
Grant	Functional Assays to Screen Genomic Hits
Grant	Gene Expression Networks for Human Cardiac Differentiation in Down Syndrome
Grant	Transcriptional Control of Cardiac Conduction System Function by T-box Genes
Grant	Functional Assays to Screen Genomic Hits
Grant	Etiology of Congenital Heart Disease in Down Syndrome
Academic Article	The cGAS-STING pathway is dispensable in a mouse model of LMNA-cardiomyopathy despite nuclear envelope rupture.
Academic Article	An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract.
Grant	Evaluation of Hedgehog Signaling-Dependent Heart Development in a Mouse Model of Down Syndrome
Academic Article	A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.

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